For elucidating the
This is associated with onset of protein folding diseases such as neurodegenerative diseases.
In other words, the intermediate stage is the turning point between normality and abnormality.
In this state, the structure is not yet fully stable, and the segment which normally forms the helix structure rarely misfolds to form the β-sheet structure.
This results in aggregation of protein, leading to formation of amyloid fibril, and loss of normal protein function.
It conducts the mind to no firm resting place; it bewilders instead of elucidating our notions of God, of man, and the universe.
However it may be, we will for the present leave to others the task of elucidating the question of origin.
We focus first on the problem of admixture inference and describe two new methods for determining the dates, sources, and proportions of ancestral mixtures between diverged populations.
I will describe our efforts to develop and integrate sets of tools that are designed to throw light on the evolution, structure and function of these macromolecular machines.
At the very earliest stage of analysis, we define the precise ensembles of macromolecular players that make up the assemblies of interest.
But that is not the question; the problem I have to elucidate!
I do not know, sire; but it may elucidate the point if I inform your majesty of a curious statement she made to me.